Transcriptional control of adipocyte formation
نویسندگان
چکیده
منابع مشابه
Hormonal signaling and transcriptional control of adipocyte differentiation.
Recent advances regarding the biology of adipose tissue have identified the adipocyte as an important mediator in many physiologic and pathologic processes regarding energy metabolism. Consideration for a central role of adipose tissue in the development of obesity, cardiovascular disease and noninsulin-dependent diabetes mellitus has resulted in new incentives toward understanding the complexi...
متن کاملSymposium: Adipocyte Function, Differentiation and Metabolism Hormonal Signaling and Transcriptional Control of Adipocyte Differentiation
Recent advances regarding the biology of adipose tissue have identified the adipocyte as an important mediator in many physiologic and pathologic processes regarding energy metabolism. Consideration for a central role of adipose tissue in the development of obesity, cardiovascular disease and noninsulin-dependent diabetes mellitus has resulted in new incentives toward understanding the complexi...
متن کاملTranscriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6
Jumonji domain-containing protein 6 (JMJD6) is a nuclear protein involved in histone modification, transcription and RNA processing. Although JMJD6 is crucial for tissue development, the link between its molecular functions and its roles in any given differentiation process is unknown. We report that JMJD6 is required for adipogenic gene expression and differentiation in a manner independent of...
متن کاملTranscriptional networks controlling adipocyte differentiation.
Adipocyte differentiation is regulated by a complex cascade of signals that drive the transcriptional reprogramming of the fibroblastic precursors. Genome-wide analyses of chromatin accessibility and binding of adipogenic transcription factors make it possible to generate "snapshots" of the transcription factor networks operating at specific time points during adipogenesis. Using such global "s...
متن کاملTranscriptional control of brown adipocyte development and physiological function--of mice and men.
The last several years have seen an explosion of information relating to the transcriptional control of brown fat cell development. At the same time, new data have emerged that clearly demonstrate that adult humans do indeed have substantial amounts of functioning brown adipose tissue (BAT). Together, these advances are stimulating a reassessment of the role of brown adipose tissue in human phy...
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2006
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2006.07.001